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Is operational research delivering the goods? The journey to success in low-income countries (Lancet)
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Is operational research delivering the goods? The journey to success in low-income countries (Lancet)
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Operational Research in Low-income Countries: What, Why, and How? (Lancet)
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Operational Research in Low-income Countries: What, Why, and How? (Lancet)
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The Union and MFS Approach to Operational Research
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The Union and MFS Approach to Operational Research
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SAMU Supported Publications: Quarter 4, 2019
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GeneXpert and Community Health Workers Supported Patient Tracing for TB Diagnosis in India
Feasibility of using Determine TB-LAM to diagnose tuberculosis in HIV-positive patients in programmatic conditions
Standardised shorter regimens versus individualised longer regimens for multidrug-resistant tuberculosis
HIV viral load algorithm: what are the needs in the field?
Diagnostic sensitivity of SILVAMP TB-LAM (FujiLAM) point-of-care urine assay for extrapulmonary TB in people living with HIV
Distribution of advanced HIV disease from three high HIV prevalence settings in Sub-Saharan Africa
Barriers and solutions to finding rifampicin-resistant tuberculosis cases in older children and adolescents
Adverse events among people on delamanid for rifampicin-resistant tuberculosis in a high HIV prevalence setting
Peer Mentorship via Mobile Phones for Newly Diagnosed HIV-Positive Youths in Clinic Care in Khayelitsha, South Africa
Southern African HIV Clinicians Society guideline for the prevention, diagnosis and management of cryptococcal disease among HIV-infected persons
New opportunities in tuberculosis prevention: implications for people living with HIV
Scaling up HIV viral load monitoring in Manicaland, Zimbabwe: challenges and opportunities from the field
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SAMU Supported Publications for Quarter 4, 2021
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Rifampicin-Monoresistant Tuberculosis Is Not the Same as Multidrug-Resistant Tuberculosis_ a Descriptive Study from Khayelitsha South Africa
Mental health interventions for rifampicin-resistant tuberculosis patients with alcohol use disorders, Zhytomyr, Ukraine
Lay testing cadres and point-of-care diagnostic tests for HIV and other diseases_ An essential combination in health service delivery
Introduction of new drugs for drug-resistant TB in IRAQ
Therapeutic experiences and post-treatment health of people with rifampicin-resistant tuberculosis
Evaluating newly approved drugs for multidrug-resistant tuberculosis
Life changing events challenge the community ART Group model a qualitative research study
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SAMU Supported Publications: Quarter 1, 2020
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Lessons from the South African flucytosine access programme
Cost-effectiveness of diagnostic algorithms including lateral-flow urine lipoarabinomannan for HIV-positive patients with symptoms of tuberculosis
Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis
Injectable-free regimens containing bedaquiline, delamanid, or both for adolescents with rifampicin-resistant tuberculosis in Khayelitsha, SouthAfrica
MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network
Access to health services for men who have sex with men and transgender women in Beira, Mozambique: A qualitative study
Emerging priorities for HIV service delivery
Tailored HIV programmes and universal health coverage
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SAMU Supported Publications: Quarter 1, 2022
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Psychiatric comorbidities among patients with complex drug resistant tuberculosis in Mumbia
Outcomes of people living with HIV after hospital discharge_ a systematic review and meta-analysis, in Lancet
Increase in HIV viral suppression in KwaZulu-Natal, South Africa
Implementing a Substance-Use Screening and Intervention Program for People Living with Rifampicin-Resistant Tuberculosis
HIV Self testing Among Previously Diagnosed HIV Positive People in Khayelitsha
Early mortality during rifampicin-resistant TB treatment.
Assessment of epidemiological and genetic characteristics and clinical outcomes of resistance to bedaquiline in patients treated for rifampicin-resistant tuberculosis.
Assessment of epidemiological and genetic characteristics and clinical outcomes of resistance to bedaquiline in patients treated for rifampicin-resistant tuberculosis_
Provision of Decentralized TB Care Services
Attrition from HIV care among youth initiating ART in youth-only clinics compared with general primary healthcare clinics in Khayelitsha
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SAMU Supported Publications: Quarter 2, 2020
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Ambulatory management of pre- and extensively drug resistant tuberculosis patients with imipenem delivered through port-a-cath
The ethical imperative to relieve suffering for people with tuberculosis by ensuring access to palliative care
Routine viral load monitoring and enhanced adherence counselling at a public ART centre in Mumbai, India
Long-term virologic responses to antiretroviral therapy among HIV-positive patients entering adherence clubs in Khayelitsha, Cape Town, South Africa
Yield of Systematic Longitudinal Screening of Household Contacts of Pre-Extensively Drug Resistant (PreXDR) and Extensively Drug Resistant (XDR) Tuberculosis Patients in Mumbai, India
Improving pediatric TB diagnosis in North Kivu (DR Congo), focusing on a clinical algorithm including targeted Xpert MTB/RIF on gastric aspirates
Framework for the implementation of advanced HIV disease diagnostics in sub-Saharan Africa
Partner Notification Approaches for Sex Partners and Children of Human Immunodeficiency Virus Index Cases in Côte d'Ivoire
Preventing tuberculosis in children: A global health emergency
Retention and sustained viral suppression in HIV patients transferred to community refill centres in Kinshasa, DRC
Population-wide differentials in HIV service access and outcomes in the Western Cape for men as compared to women, South Africa: 2008 to 2018
Critical changes to services for TB patients during the COVID-19 pandemic
The Enduring Burden of Advanced Human Immunodeficiency Virus Disease
Diagnostic performance and usability of the VISITECT CD4 semi-quantitative test for advanced HIV disease screening
Setting up a nurse-led model of care for management of hypertension and diabetes mellitus in a high HIV prevalence context in rural Zimbabwe
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SAMU Supported Publications: Quarter 2, 2022
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Feasibility and acceptability of using the novel urine-based FujiLAM test to detect tuberculosis: A multi-country mixed-methods study
Being heard on all-oral therapy for resistant tuberculosis
Treatment outcomes 24 months after initiating short, all-oral bedaquiline-containing or injectable-containing rifampicin-resistant tuberculosis treatment regimens in South Africa: a retrospective cohort study
DAA treatment failures in a low-resource setting with a high burden of hepatitis C infections: a case series
Prevalence of TB and health-seeking behaviour
Causes of loss to follow-up from drug-resistant TB treatment in Khayelitsha, South Africa
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SAMU Supported Publications: Quarter 3, 2020
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OIM: Outreach initiation and Management
The problem with vitamin D supplementation for tuberculosis
The People Living with HIV Stigma Index 2.0: generating critical evidence for change worldwide
Adapting TB services during the COVID-19 pandemic in Mumbai, India
How COVID-19 could benefit tuberculosis and HIV services in South Africa
Successes and gaps in the HIV cascade of care of a high HIV prevalence setting in Zimbabwe: a population-based survey
Preparedness of outpatient health facilities for ambulatory treatment with all-oral short DR-TB treatment regimens in Zhytomyr, Ukraine: a cross-sectional study
Knowledge transmission, peer support, behaviour change and satisfaction in post Natal clubs in Khayelitsha, South Africa: a qualitative study
Responding to SARS-CoV-2 in South Africa: what can we learn from drug- resistant tuberculosis?
‘Only twice a year’: a qualitative exploration of 6-month antiretroviral treatment refills in adherence clubs for people living with HIV in Khayelitsha, South Africa
Mortality in adults with multidrug-resistant tuberculosis and HIV by antiretroviral therapy and tuberculosis drug use: an individual patient data meta-analysis
Correspondence regarding “Delamanid for rifampicin-resistant tuberculosis: a retrospective study from South Africa”
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SAMU Supported Publications: Quarter 4, 2020
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Safety and effectiveness of an all-oral, bedaquiline-based, shorter treatment regimen for rifampicin-resistant tuberculosis in high HIV burden rural South Africa: a retrospective cohort analysis
Twenty-four-month outcomes from a cluster-randomized controlled trial of extending antiretroviral therapy refills in ART adherence clubs
New TB drugs for the treatment of children and adolescents with rifampicin-resistant TB in Mumbai, India
Ending deaths from HIV-related cryptococcal meningitis by 2030
Southern African HIV Clinicians Society guidelines for antiretroviral therapy in adults: 2020 update
Adapting TB services during the COVID-19 pandemic in Mumbai, India
“SILVAMP TB LAM” Rapid Urine Tuberculosis Test Predicts Mortality in Patients Hospitalized With Human Immunodeficiency Virus in South Africa
Clinical perspectives on treatment of rifampicin-resistant/ multidrug-resistant TB
Implementing novel regimens for drug-resistant TB in South Africa: what can the world learn?
One step forward: Successful end-of-treatment outcomes of drugresistant TB patients who received concomitant bedaquiline and delamanid in Mumbai, India
Impact of the implementation of new guidelines on the management of patients with HIV infection at an advanced HIV clinic in Kinshasa, Democratic Republic of Congo (DRC)
Mumbai team on new TB drugs for the treatment of children and adolescents, published in IJTLD
Eshowe team on the all-oral, bedaquiline based, shorter regime, published online in CID
Khayelistsha team on the 6 month refills RCT, published in JIAS
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SAMU Supported Publications: Quarter 1, 2019
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Beyond 'cure' and 'treatment success': quality of life of patients with multidrug-resistant tuberculosis
Delays in seeking care and treatment for advanced HIV disease in Kinshasa, DRC
Mortality in the first six months among HIV-positive and HIV-negative patients empirically treated for tuberculosis.
The Continuing Value of CD4 Cell Count Monitoring for Differential HIV Care and Surveillance
Demanding an end to tuberculosis: treatment of tuberculosis infection among persons living with and without HIV
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SAMU Supported Publications Quarter 1, 2021
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“It’s a secret between us”: a qualitative study on children and care-giver experiences of HIV disclosure in Kinshasa, Democratic Republic of Congo
Treatment outcomes of children and adolescents receiving drug-resistant TB treatment in a routine TB programme, Mumbai, India
Tuberculosis preventive therapy for children and adolescents: an emergency response to the COVID-19 pandemic
A positive COVID-19 test is associated with high mortality in RR-TB-HIV patients
Challenging drug-resistant TB treatment journey for children, adolescents and their care-givers: A qualitative study
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SAMU Supported Publications: Quarter 2, 2019
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Bedaquiline and delamanid in combination for treatment of drugresistant tuberculosis
Patient and health-care worker experiences of an HIV viral load intervention using SMS: A qualitative study
Bedaquiline Microheteroresistance after Cessation of Tuberculosis Treatment
The STREAM trial: missed opportunities and lessons for future clinical trials
Investigating the addition of oral HIV self-tests among populations with high testing coverage
Outcomes of patients in clubs after recent viral suppression
Simplifying switch to second-line antiretroviral therapy
Breast Tuberculosis in Women: A systematic Review
The missed potential of CD4 and viral load testing
ART adherence clubs in Khayelitsha and Gugulethu
HIV virological failure in Mozambique
Performance of Cepheid GeneXpert HIV-1 viral load plasma assay to accurately detect treatment failure
Universal regimens or universal access to drug susceptibility testing for tuberculosis?
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SAMU Supported Publications Quarter 2, 2021
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What gaps remain in the HIV cascade of care? Results of a population- based survey in Nsanje District, Malawi
A positive COVID-19 test is associated with high mortality in RR-TB-HIV patients
Community-based TB testing as an essential part of TB recovery plans in the COVID-19 era
Treating Drug-resistant Tuberculosis Infection: No More Excuses
High Prevalence of NRTI and NNRTI Drug Resistance Among ART-Experienced, Hospitalized Inpatients
OCB Medical Activity Report 2020
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SAMU Supported Publications: Quarter 3, 2019
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A cluster randomized controlled trial of extending ART refill intervals to six-monthly for anti-retroviral adherence clubs
Challenges and controversies in childhood tuberculosis
The epidemiology of rape and sexual violence in the platinum mining district of Rustenburg, South Africa: Prevalence, and factors associated with sexual violence
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SAMU Supported Publications for Quarter 3, 2021
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The HIV cascade of care among serodiscordant couples in four high HIV prevalence settings in sub-Saharan Africa
Correction to: Delivering PrEP to Young Women in a Low‑Income Setting in South Africa: Lessons for Providing Both Convenience and Support
Delivering PrEP to Young Women in a Low‐Income Setting in South Africa: Lessons for Providing Both Convenience and Support
A home-based care programme for rifampicin-resistant TB
High Prevalence of NRTI and NNRTI Drug Resistance Among ART-Experienced
Virologic efficacy of tenofovir, lamivudine and dolutegravir as second-line antiretroviral therapy in adults failing a tenofovir-based first-line regimen
Diagnosis patterns for rifampicin-resistant TB after onset of COVID-19
Slipping through the cracks: a qualitative study to explore pathways of HIV care and treatment amongst hospitalised patients with advanced HIV in Kenya and the Democratic Republic of the Congo
Rifampicin mono-resistant tuberculosis is not the same as multidrug-resistant tuberculosis: a descriptive study from Khayelitsha, South Africa
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OCB Scientific Publications
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OCB Scientific Publications 2017
OCB Scientific Publications 2016
OCB Scientific Publications 2015
OCB Scientific Publications 2014
OCB Scientific Publications 2013
SAMU Summary: Operational Research
MSF ERB Ethics Review Research Template
Application for Extension of Ethics Approval
Exemption Criteria: Retrospective Routine Data
Declaration of End of Study
Request for Amendment Approval
MSF ERB Ethics Review Research Template
MSF Research Ethics Framework - Guidance Document
Is operational research delivering the goods? The journey to success in low-income countries (Lancet)
Operational Research in Low-income Countries: What, Why, and How? (Lancet)
GeneXpert and Community Health Workers Supported Patient Tracing for TB Diagnosis in India
Feasibility of using Determine TB-LAM to diagnose tuberculosis in HIV-positive patients in programmatic conditions
Standardised shorter regimens versus individualised longer regimens for multidrug-resistant tuberculosis
HIV viral load algorithm: what are the needs in the field?
Diagnostic sensitivity of SILVAMP TB-LAM (FujiLAM) point-of-care urine assay for extrapulmonary TB in people living with HIV
Distribution of advanced HIV disease from three high HIV prevalence settings in Sub-Saharan Africa
Barriers and solutions to finding rifampicin-resistant tuberculosis cases in older children and adolescents
Adverse events among people on delamanid for rifampicin-resistant tuberculosis in a high HIV prevalence setting
Peer Mentorship via Mobile Phones for Newly Diagnosed HIV-Positive Youths in Clinic Care in Khayelitsha, South Africa
Southern African HIV Clinicians Society guideline for the prevention, diagnosis and management of cryptococcal disease among HIV-infected persons
New opportunities in tuberculosis prevention: implications for people living with HIV
Scaling up HIV viral load monitoring in Manicaland, Zimbabwe: challenges and opportunities from the field
Rifampicin-Monoresistant Tuberculosis Is Not the Same as Multidrug-Resistant Tuberculosis_ a Descriptive Study from Khayelitsha South Africa
Cost-effectiveness of diagnostic algorithms including lateral-flow urine lipoarabinomannan for HIV-positive patients with symptoms of tuberculosis
Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis
Injectable-free regimens containing bedaquiline, delamanid, or both for adolescents with rifampicin-resistant tuberculosis in Khayelitsha, SouthAfrica
MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network
Access to health services for men who have sex with men and transgender women in Beira, Mozambique: A qualitative study
Tailored HIV programmes and universal health coverage
Ambulatory management of pre- and extensively drug resistant tuberculosis patients with imipenem delivered through port-a-cath
The ethical imperative to relieve suffering for people with tuberculosis by ensuring access to palliative care
Routine viral load monitoring and enhanced adherence counselling at a public ART centre in Mumbai, India
Long-term virologic responses to antiretroviral therapy among HIV-positive patients entering adherence clubs in Khayelitsha, Cape Town, South Africa
Yield of Systematic Longitudinal Screening of Household Contacts of Pre-Extensively Drug Resistant (PreXDR) and Extensively Drug Resistant (XDR) Tuberculosis Patients in Mumbai, India
Improving pediatric TB diagnosis in North Kivu (DR Congo), focusing on a clinical algorithm including targeted Xpert MTB/RIF on gastric aspirates
Framework for the implementation of advanced HIV disease diagnostics in sub-Saharan Africa
Partner Notification Approaches for Sex Partners and Children of Human Immunodeficiency Virus Index Cases in Côte d'Ivoire
Preventing tuberculosis in children: A global health emergency
Retention and sustained viral suppression in HIV patients transferred to community refill centres in Kinshasa, DRC
Population-wide differentials in HIV service access and outcomes in the Western Cape for men as compared to women, South Africa: 2008 to 2018
Critical changes to services for TB patients during the COVID-19 pandemic
The Enduring Burden of Advanced Human Immunodeficiency Virus Disease
Diagnostic performance and usability of the VISITECT CD4 semi-quantitative test for advanced HIV disease screening
Setting up a nurse-led model of care for management of hypertension and diabetes mellitus in a high HIV prevalence context in rural Zimbabwe
The People Living with HIV Stigma Index 2.0: generating critical evidence for change worldwide
Adapting TB services during the COVID-19 pandemic in Mumbai, India
How COVID-19 could benefit tuberculosis and HIV services in South Africa
Successes and gaps in the HIV cascade of care of a high HIV prevalence setting in Zimbabwe: a population-based survey
Preparedness of outpatient health facilities for ambulatory treatment with all-oral short DR-TB treatment regimens in Zhytomyr, Ukraine: a cross-sectional study
Knowledge transmission, peer support, behaviour change and satisfaction in post Natal clubs in Khayelitsha, South Africa: a qualitative study
Responding to SARS-CoV-2 in South Africa: what can we learn from drug- resistant tuberculosis?
‘Only twice a year’: a qualitative exploration of 6-month antiretroviral treatment refills in adherence clubs for people living with HIV in Khayelitsha, South Africa
Mortality in adults with multidrug-resistant tuberculosis and HIV by antiretroviral therapy and tuberculosis drug use: an individual patient data meta-analysis
Correspondence regarding “Delamanid for rifampicin-resistant tuberculosis: a retrospective study from South Africa”
Beyond 'cure' and 'treatment success': quality of life of patients with multidrug-resistant tuberculosis
Delays in seeking care and treatment for advanced HIV disease in Kinshasa, DRC
Mortality in the first six months among HIV-positive and HIV-negative patients empirically treated for tuberculosis.
The Continuing Value of CD4 Cell Count Monitoring for Differential HIV Care and Surveillance
Demanding an end to tuberculosis: treatment of tuberculosis infection among persons living with and without HIV
Bedaquiline and delamanid in combination for treatment of drugresistant tuberculosis
Patient and health-care worker experiences of an HIV viral load intervention using SMS: A qualitative study
The STREAM trial: missed opportunities and lessons for future clinical trials
Investigating the addition of oral HIV self-tests among populations with high testing coverage
Outcomes of patients in clubs after recent viral suppression
Performance of Cepheid GeneXpert HIV-1 viral load plasma assay to accurately detect treatment failure
Universal regimens or universal access to drug susceptibility testing for tuberculosis?
A cluster randomized controlled trial of extending ART refill intervals to six-monthly for anti-retroviral adherence clubs
The epidemiology of rape and sexual violence in the platinum mining district of Rustenburg, South Africa: Prevalence, and factors associated with sexual violence
